These studies use the endochondral pathway to engineer growing bone for correction of craniofacial defects. We are conducting both in vitro and in vivo studies.
These studies investigate novel transcription factors and other molecules regulating endochondral and intramembranous ossification both in vitro, in vivo, and ex vivo.
The response of hard and soft tissues to orthodontic forces is being studied at the molecular level. These projects are conducted in both animals and humans.
Human and animal tooth movement models are being used to investigate the effect of cytokine expression on the rate of bone remodeling and tooth movement (Patent pending).